Shoaib received his BDS from de’Montmorency College of Dentistry, Lahore in 2003. After completing the house job, he moved towards fundamental research and earned his M.Sc. in Molecular Oncology in 2006 and Ph.D. in Molecular Biology in 2011, both from the Gustave Roussy Cancer-Campus, University of Paris-Sud, France. In 2013, he received a postdoctoral fellowship from the Villum Foundation, Denmark, and worked at the Biotech Research and Innovation Center (BRIC), University of Copenhagen, a global hub for research in genome stability and DNA repair. In 2018, his project received a large grant from the Novo Nordisk Foundation and he was promoted to Assistant Professor at the University of Copenhagen, Denmark, where he worked until March 2021.

Shoaib joined the Department of Life Sciences at Syed Babar Ali School of Science and Engineering in April 2021 as an Associate Professor and established Epigenome and Genome Integrity Lab (EaGIL). He studies chromatin biology and its interplay with genome maintenance pathways. Using Systems Biology approaches, his research group aims to build next-generation multiscale in silico networks of epigenetic and DNA damage response factors and annotate these biomolecular networks with patient-specific mutations and gene expression data towards developing personalized cancer therapies.