Research Interests
Sajjal Waqas, an MS student, worked on the PUB-UBL system to investigate the role of NEDD8, a ubiquitin-like modifier, during DNA replication stress. She designed and cloned guide RNAs and homologous recombination templates for CRISPR-based editing of the endogenous NEDD8 locus. Her research aimed to enable proximity-based labeling and functional analysis of NEDD8-modified proteins involved in the replication stress response.
Keywords
NEDD8, PUB-UBL, CRISPR-based genome editing